Sisters Blake and Jamie's big plans for the year 2020 come to a screeching halt when they are forced to rescue their grandmother and her beloved dog from her nursing home, as COVID attacks. They embark on a hilarious, cross-country race against time to beat their irresponsible sister getting there first. On the road the free-spirited pair is contending with a deranged dog breeder, a highly inappropriate 9-year-old boy, and a clueless Tinder hook-up, all in the name of family.